Globulin, Total
Total globulin captures the family of blood proteins other than albumin. It includes immunoglobulins (antibodies), transport proteins, clotting factors, and other carrier proteins. The value is calculated from total protein minus albumin.
Why it matters: Higher total globulin can be seen with chronic inflammation or infection, because antibody levels rise. Lower globulin is less common and is interpreted alongside immunoglobulin subclass measurements when relevant.
May increase with:
May decrease with:
What is Globulin, Total?
Total globulin captures the family of blood proteins other than albumin. It includes immunoglobulins (antibodies), transport proteins, clotting factors, and other carrier proteins. The value is calculated from total protein minus albumin.
What might a high or low Globulin, Total mean?
Higher total globulin can be seen with chronic inflammation or infection, because antibody levels rise. Lower globulin is less common and is interpreted alongside immunoglobulin subclass measurements when relevant.
What can affect Globulin, Total?
It may be higher with: Chronic inflammation, Infection, Autoimmune disease. It may be lower with: Liver disease, Malnutrition.
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