Bilirubin (Direct)

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Direct bilirubin mainly reflects the bilirubin the liver has already processed, known as conjugated bilirubin. It is water-soluble and can be measured directly.

Why it matters: A higher level of conjugated bilirubin can appear when the body is having trouble clearing it, which might indicate a biliary or gallstone disease.

Source · Cleveland Clinic — what it is, why it matters, related conditions

Reference Range
< 5.0umol/L
5NormalHigh
Associated Conditions
GallstonesCholecystitisCholangitis
Related Markers
Bilirubin (Total)Alkaline PhosphataseGGT
Common questions

What is Bilirubin (Direct)?

Direct bilirubin mainly reflects the bilirubin the liver has already processed, known as conjugated bilirubin. It is water-soluble and can be measured directly.

What might a high or low Bilirubin (Direct) mean?

A higher level of conjugated bilirubin can appear when the body is having trouble clearing it, which might indicate a biliary or gallstone disease.

What is the typical reference range for Bilirubin (Direct)?

The general-population reference range shown here is < 5 umol/L. Reference ranges describe the general population and are not a personal target — discuss your results with your physician.

More in Liver
AlbuminAlkaline PhosphataseALTASTBilirubin (Indirect)Bilirubin (Total)GGTLDH

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