IGF-1

Growth HormonesHormonal BalanceBlood

IGF-1 (Insulin-like Growth Factor 1) mediates growth hormone effects on tissue growth, muscle development, and bone formation.

Why it matters: Standard screening marker for growth hormone disorders. Declines with age; researched in aging and longevity contexts.

Reference Range
115.0 – 355.0ng/mL
115
355LowNormalHigh
Symptoms of Low IGF-1
Fatigue, reduced muscle mass
Increased body fat
Symptoms of High IGF-1
Enlarged hands/feet/facial features (acromegaly)
Joint pain
What Moves It

May increase with:

Growth hormone
Protein intake
Resistance training
Sleep

May decrease with:

Aging
Malnutrition
Liver disease
GH deficiency
Associated Conditions
Growth hormone deficiencyAcromegalyAging
Related Markers
Testosterone (Total)Insulin
Common questions

What is IGF-1?

IGF-1 (Insulin-like Growth Factor 1) mediates growth hormone effects on tissue growth, muscle development, and bone formation.

What might a high or low IGF-1 mean?

Standard screening marker for growth hormone disorders. Declines with age; researched in aging and longevity contexts.

What is the typical reference range for IGF-1?

The general-population reference range shown here is 115 – 355 ng/mL. Reference ranges describe the general population and are not a personal target — discuss your results with your physician.

What can affect IGF-1?

It may be higher with: Growth hormone, Protein intake, Resistance training, Sleep. It may be lower with: Aging, Malnutrition, Liver disease, GH deficiency.

Track your IGF-1 over time

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