SHBG

Sex HormonesHormonal BalanceBlood

Sex hormone-binding globulin, or SHBG, is a protein that carries androgens — testosterone and DHT — and estrogen in the blood.

Why it matters: In females, providers typically use the free androgen index to check for high androgen levels, and that index starts with a blood test measuring total testosterone, free testosterone and SHBG. A provider compares total testosterone to SHBG to find the amount of androgen in the blood.

Source · Cleveland Clinic — what it is, why it matters

Reference Range
18.3 – 54.1nmol/L
18.3
54.1LowNormalHigh
Related Markers
Testosterone (Total)Free TestosteroneEstradiol
Common questions

What is SHBG?

Sex hormone-binding globulin, or SHBG, is a protein that carries androgens — testosterone and DHT — and estrogen in the blood.

What might a high or low SHBG mean?

In females, providers typically use the free androgen index to check for high androgen levels, and that index starts with a blood test measuring total testosterone, free testosterone and SHBG. A provider compares total testosterone to SHBG to find the amount of androgen in the blood.

What is the typical reference range for SHBG?

The general-population reference range shown here is 18.3 – 54.1 nmol/L. Reference ranges describe the general population and are not a personal target — discuss your results with your physician.

More in Sex Hormones
EstradiolFree TestosteroneFSHLHProgesteroneProlactinTestosterone (Total)

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