Anti-TPO

ThyroidThyroidBlood

Thyroid peroxidase antibodies are the main antibody that signals Hashimoto's disease.

Why it matters: A high level indicates the immune system has attacked cells in the thyroid. Alongside a raised TSH this suggests Hashimoto's disease; with a normal or near-normal TSH it may mean hypothyroidism develops later.

Source · Cleveland Clinic — what it is, why it matters, related conditions

Reference Range
< 34.0IU/mL
34NormalHigh
Associated Conditions
Hashimoto's disease, where a positive result accompanies a high TSH
Related Markers
TSHFree T3Free T4
Common questions

What is Anti-TPO?

Thyroid peroxidase antibodies are the main antibody that signals Hashimoto's disease.

What might a high or low Anti-TPO mean?

A high level indicates the immune system has attacked cells in the thyroid. Alongside a raised TSH this suggests Hashimoto's disease; with a normal or near-normal TSH it may mean hypothyroidism develops later.

What is the typical reference range for Anti-TPO?

The general-population reference range shown here is < 34 IU/mL. Reference ranges describe the general population and are not a personal target — discuss your results with your physician.

More in Thyroid
Anti-ThyroglobulinCalcitoninFree T3Free T4Free Thyroxine Index (T7)T3 (Total)T3 UptakeT4 (Total)TSHTSH Receptor Antibodies

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