Calcitonin

ThyroidThyroidBlood

Calcitonin is a hormone made by C-cells in the thyroid gland. It plays a small role in fine-tuning blood calcium levels, although other hormones (parathyroid hormone, vitamin D) do most of the calcium-regulation work in the body.

Why it matters: Calcitonin is most relevant when reviewing thyroid nodules with specific patterns. Routine calcium-status review usually relies on calcium, parathyroid hormone, and vitamin D — calcitonin contributes specialized context when needed.

Reference Range
< 8.4pg/mL
8.4NormalHigh
Symptoms of Low Calcitonin
Typically without noticeable symptoms
Symptoms of High Calcitonin
Typically without noticeable symptoms; very high levels can be associated with neck lump or flushing
What Moves It

May increase with:

Medullary thyroid cancer
C-cell hyperplasia
Kidney disease
Pregnancy

May decrease with:

Thyroidectomy
Advanced age
Associated Conditions
Medullary thyroid cancerMultiple endocrine neoplasia type 2C-cell hyperplasia
Related Markers
CalciumPTHceaTSH
Common questions

What is Calcitonin?

Calcitonin is a hormone made by C-cells in the thyroid gland. It plays a small role in fine-tuning blood calcium levels, although other hormones (parathyroid hormone, vitamin D) do most of the calcium-regulation work in the body.

What might a high or low Calcitonin mean?

Calcitonin is most relevant when reviewing thyroid nodules with specific patterns. Routine calcium-status review usually relies on calcium, parathyroid hormone, and vitamin D — calcitonin contributes specialized context when needed.

What is the typical reference range for Calcitonin?

The general-population reference range shown here is < 8.4 pg/mL. Reference ranges describe the general population and are not a personal target — discuss your results with your physician.

What can affect Calcitonin?

It may be higher with: Medullary thyroid cancer, C-cell hyperplasia, Kidney disease, Pregnancy. It may be lower with: Thyroidectomy, Advanced age.

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