MCH
Mean corpuscular hemoglobin (MCH) measures the average amount of hemoglobin per red blood cell in picograms. It reflects how well each RBC is loaded with hemoglobin. MCH generally parallels MCV — small cells (low MCV) carry less hemoglobin (low MCH) and vice versa.
Why it matters: Low MCH (hypochromic) indicates cells are under-filled with hemoglobin, typically from iron deficiency. High MCH (hyperchromic) accompanies macrocytic anemias. While MCH provides similar information to MCV, the combination of MCH and MCHC helps distinguish between different types of microcytic anemia.
May increase with:
May decrease with:
What is MCH?
Mean corpuscular hemoglobin (MCH) measures the average amount of hemoglobin per red blood cell in picograms. It reflects how well each RBC is loaded with hemoglobin. MCH generally parallels MCV — small cells (low MCV) carry less hemoglobin (low MCH) and vice versa.
What might a high or low MCH mean?
Low MCH (hypochromic) indicates cells are under-filled with hemoglobin, typically from iron deficiency. High MCH (hyperchromic) accompanies macrocytic anemias. While MCH provides similar information to MCV, the combination of MCH and MCHC helps distinguish between different types of microcytic anemia.
What is the typical reference range for MCH?
The general-population reference range shown here is 27 – 34 pg. Reference ranges describe the general population and are not a personal target — discuss your results with your physician.
What can affect MCH?
It may be higher with: B12 deficiency, Folate deficiency, Chronic alcohol use, Hypothyroidism, Reticulocytosis. It may be lower with: Iron deficiency, Thalassemia, Chronic disease anemia, Lead poisoning.