C-Peptide
C-peptide is released 1:1 with insulin production. Unlike insulin, it is not cleared by the liver, making it a stable marker of endogenous insulin production.
Why it matters: Helps distinguish Type 1 (low C-peptide) from Type 2 diabetes (normal/high C-peptide). Used to evaluate insulinoma.
May increase with:
May decrease with:
What is C-Peptide?
C-peptide is released 1:1 with insulin production. Unlike insulin, it is not cleared by the liver, making it a stable marker of endogenous insulin production.
What might a high or low C-Peptide mean?
Helps distinguish Type 1 (low C-peptide) from Type 2 diabetes (normal/high C-peptide). Used to evaluate insulinoma.
What is the typical reference range for C-Peptide?
The general-population reference range shown here is 1.1 – 4.4 ng/mL. Reference ranges describe the general population and are not a personal target — discuss your results with your physician.
What can affect C-Peptide?
It may be higher with: Insulin resistance, Type 2 diabetes, Insulinoma. It may be lower with: Type 1 diabetes, Late-stage type 2 diabetes, Pancreatectomy.
Track your C-Peptide over time
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