HbA1c (IFCC)

MetabolicMetabolism & EnergyBlood

HbA1c (IFCC) is the same measurement as HbA1c but expressed in millimoles per mole (mmol/mol) using the International Federation of Clinical Chemistry standard, rather than the traditional DCCT percentage. The IFCC method is considered more standardized and is used in many European and international laboratories.

Why it matters: IFCC HbA1c and DCCT HbA1c measure the same thing — the two values are mathematically interconvertible. The IFCC standard was developed to improve measurement consistency across laboratories worldwide. Both formats are equally valid for diabetes management.

Reference Range
< 42.0mmol/mol
42NormalHigh
Symptoms of Low HbA1c (IFCC)
May reflect frequent low blood sugar episodes
Symptoms of High HbA1c (IFCC)
Same as HbA1c — reflects long-term blood sugar elevation
What Moves It

May increase with:

High blood sugar
Diabetes
Prediabetes

May decrease with:

Low-carb diet
Weight loss
Exercise
Diabetes medications
Associated Conditions
Type 2 diabetesPrediabetesMetabolic syndrome
Related Markers
GlucoseInsulinHbA1c
Common questions

What is HbA1c (IFCC)?

HbA1c (IFCC) is the same measurement as HbA1c but expressed in millimoles per mole (mmol/mol) using the International Federation of Clinical Chemistry standard, rather than the traditional DCCT percentage. The IFCC method is considered more standardized and is used in many European and international laboratories.

What might a high or low HbA1c (IFCC) mean?

IFCC HbA1c and DCCT HbA1c measure the same thing — the two values are mathematically interconvertible. The IFCC standard was developed to improve measurement consistency across laboratories worldwide. Both formats are equally valid for diabetes management.

What is the typical reference range for HbA1c (IFCC)?

The general-population reference range shown here is < 42 mmol/mol. Reference ranges describe the general population and are not a personal target — discuss your results with your physician.

What can affect HbA1c (IFCC)?

It may be higher with: High blood sugar, Diabetes, Prediabetes. It may be lower with: Low-carb diet, Weight loss, Exercise, Diabetes medications.

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