HDL Cholesterol
High-density lipoprotein (HDL) performs reverse cholesterol transport — collecting excess cholesterol from arterial walls and peripheral tissues and returning it to the liver for excretion. HDL also has anti-inflammatory, antioxidant, and antithrombotic properties that protect the cardiovascular system beyond simple cholesterol removal.
Why it matters: Low HDL is associated with higher cardiovascular risk. Interestingly, raising HDL with medication has not consistently reduced cardiovascular events, which suggests how well HDL functions may matter more than the amount alone.
May increase with:
May decrease with:
What is HDL Cholesterol?
High-density lipoprotein (HDL) performs reverse cholesterol transport — collecting excess cholesterol from arterial walls and peripheral tissues and returning it to the liver for excretion. HDL also has anti-inflammatory, antioxidant, and antithrombotic properties that protect the cardiovascular system beyond simple cholesterol removal.
What might a high or low HDL Cholesterol mean?
Low HDL is associated with higher cardiovascular risk. Interestingly, raising HDL with medication has not consistently reduced cardiovascular events, which suggests how well HDL functions may matter more than the amount alone.
What is the typical reference range for HDL Cholesterol?
The general-population reference range shown here is > 1 mmol/L. Reference ranges describe the general population and are not a personal target — discuss your results with your physician.
What can affect HDL Cholesterol?
It may be higher with: Regular aerobic exercise (strongest lifestyle factor), Weight loss, Moderate alcohol consumption (1 drink/day), Omega-3 fatty acids (fish oil), Monounsaturated fats (olive oil, avocado), Smoking cessation, Niacin (vitamin B3), Coconut oil (modest effect). It may be lower with: Smoking, Sedentary lifestyle, Trans fats, Very low-fat diets, Obesity and insulin resistance, Anabolic steroids, Beta-blockers, Uncontrolled diabetes.
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