HDL Cholesterol

Lipid PanelHeart & VesselsBlood

High-density lipoprotein (HDL) performs reverse cholesterol transport — collecting excess cholesterol from arterial walls and peripheral tissues and returning it to the liver for excretion. HDL also has anti-inflammatory, antioxidant, and antithrombotic properties that protect the cardiovascular system beyond simple cholesterol removal.

Why it matters: Low HDL is associated with higher cardiovascular risk. Interestingly, raising HDL with medication has not consistently reduced cardiovascular events, which suggests how well HDL functions may matter more than the amount alone.

Reference Range
> 1.0mmol/L
1LowNormal
Symptoms of Low HDL Cholesterol
Typically without noticeable symptoms
Symptoms of High HDL Cholesterol
Typically without noticeable symptoms
What Moves It

May increase with:

Regular aerobic exercise (strongest lifestyle factor)
Weight loss
Moderate alcohol consumption (1 drink/day)
Omega-3 fatty acids (fish oil)
Monounsaturated fats (olive oil, avocado)
Smoking cessation
Niacin (vitamin B3)
Coconut oil (modest effect)

May decrease with:

Smoking
Sedentary lifestyle
Trans fats
Very low-fat diets
Obesity and insulin resistance
Anabolic steroids
Beta-blockers
Uncontrolled diabetes
Associated Conditions
Cardiovascular diseaseMetabolic syndromeType 2 diabetesFamilial HDL deficiencyTangier disease
Related Markers
LDL CholesterolTriglyceridesTotal CholesterolApolipoprotein B
Common questions

What is HDL Cholesterol?

High-density lipoprotein (HDL) performs reverse cholesterol transport — collecting excess cholesterol from arterial walls and peripheral tissues and returning it to the liver for excretion. HDL also has anti-inflammatory, antioxidant, and antithrombotic properties that protect the cardiovascular system beyond simple cholesterol removal.

What might a high or low HDL Cholesterol mean?

Low HDL is associated with higher cardiovascular risk. Interestingly, raising HDL with medication has not consistently reduced cardiovascular events, which suggests how well HDL functions may matter more than the amount alone.

What is the typical reference range for HDL Cholesterol?

The general-population reference range shown here is > 1 mmol/L. Reference ranges describe the general population and are not a personal target — discuss your results with your physician.

What can affect HDL Cholesterol?

It may be higher with: Regular aerobic exercise (strongest lifestyle factor), Weight loss, Moderate alcohol consumption (1 drink/day), Omega-3 fatty acids (fish oil), Monounsaturated fats (olive oil, avocado), Smoking cessation, Niacin (vitamin B3), Coconut oil (modest effect). It may be lower with: Smoking, Sedentary lifestyle, Trans fats, Very low-fat diets, Obesity and insulin resistance, Anabolic steroids, Beta-blockers, Uncontrolled diabetes.

More in Lipid Panel
ApoB/ApoA1 RatioApolipoprotein A1Apolipoprotein BLDL CholesterolLipoprotein(a)Non-HDL CholesterolRemnant CholesterolTotal CholesterolTriglyceridesVLDL Cholesterol

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