LDL Cholesterol

What is LDL Cholesterol?

Low-density lipoprotein (LDL) is the primary carrier of cholesterol to peripheral tissues. LDL particles penetrate the arterial wall where they become oxidized, triggering an inflammatory response that forms atherosclerotic plaques. The number and size of LDL particles matter — small dense LDL is more atherogenic than large buoyant LDL.

What might a high or low LDL Cholesterol mean?

Elevated LDL is one of the most important modifiable factors associated with cardiovascular disease. LDL particles can accumulate in the artery wall over time, and higher levels sustained over many years are associated with greater cumulative arterial change.

What is the typical reference range for LDL Cholesterol?

The general-population reference range shown here is < 3 mmol/L. Reference ranges describe the general population and are not a personal target — discuss your results with your physician.

What can affect LDL Cholesterol?

It may be higher with: Saturated fat intake (red meat, cheese, butter), Trans fats (partially hydrogenated oils), Sedentary lifestyle, Genetic predisposition (familial hypercholesterolemia), Hypothyroidism, Kidney disease (nephrotic syndrome), Excess dietary cholesterol, Obesity and insulin resistance. It may be lower with: Soluble fiber (oats, beans, psyllium), Regular aerobic exercise, Statins and other lipid-lowering medications, Weight loss, Plant sterols/stanols, PCSK9 inhibitors, Mediterranean diet pattern, Replacing saturated with unsaturated fats.