Remnant Cholesterol

What is Remnant Cholesterol?

Remnant cholesterol represents cholesterol carried in triglyceride-rich remnant lipoproteins — partially metabolized VLDL and chylomicron particles. These remnants are small enough to penetrate the arterial wall (like LDL) but are taken up by macrophages even more efficiently, making them highly atherogenic.

What might a high or low Remnant Cholesterol mean?

Elevated remnant cholesterol is an independent causal risk factor for cardiovascular disease and low-grade inflammation. Genetic studies (Mendelian randomization) show that remnant cholesterol may be as atherogenic as LDL cholesterol on a per-particle basis. It explains residual cardiovascular risk in patients with well-controlled LDL.

What is the typical reference range for Remnant Cholesterol?

The general-population reference range shown here is < 0.9 mmol/L. Reference ranges describe the general population and are not a personal target — discuss your results with your physician.

What can affect Remnant Cholesterol?

It may be higher with: High triglycerides, Metabolic syndrome and insulin resistance, Type 2 diabetes, High carbohydrate diet, Obesity, Postprandial state (after meals), Genetic factors. It may be lower with: Low-carb diet, Weight loss, Omega-3 fatty acids, Fibrates, Exercise, Improving insulin sensitivity, Reducing refined carbohydrates.