Non-HDL Cholesterol
Non-HDL cholesterol is calculated by subtracting HDL from total cholesterol. It represents all atherogenic cholesterol — LDL, VLDL, IDL, and lipoprotein(a) combined. This single number captures the total burden of cholesterol in particles that can penetrate and damage arterial walls.
Why it matters: Non-HDL captures cardiovascular risk more completely than LDL alone because it includes triglyceride-rich remnant particles. It is especially informative when triglycerides are elevated, which makes calculated LDL less accurate.
May increase with:
May decrease with:
What is Non-HDL Cholesterol?
Non-HDL cholesterol is calculated by subtracting HDL from total cholesterol. It represents all atherogenic cholesterol — LDL, VLDL, IDL, and lipoprotein(a) combined. This single number captures the total burden of cholesterol in particles that can penetrate and damage arterial walls.
What might a high or low Non-HDL Cholesterol mean?
Non-HDL captures cardiovascular risk more completely than LDL alone because it includes triglyceride-rich remnant particles. It is especially informative when triglycerides are elevated, which makes calculated LDL less accurate.
What is the typical reference range for Non-HDL Cholesterol?
The general-population reference range shown here is < 3.9 mmol/L. Reference ranges describe the general population and are not a personal target — discuss your results with your physician.
What can affect Non-HDL Cholesterol?
It may be higher with: Same factors that raise LDL and triglycerides, Saturated fat intake, Obesity, Insulin resistance, Genetic factors, Sedentary lifestyle. It may be lower with: Statins, Weight loss, Exercise, Low-carb diet, Omega-3 fatty acids, Fibrates, Dietary fiber.
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